Pediatric autoimmune encephalitis
نویسندگان
چکیده
منابع مشابه
Autoimmune Encephalitis
autoimmune encephalitis (aiE) associated with neural autoantibodies is increasingly recognized as a cause of subacute onset amnesia, confusion, and seizures. in the past decade, several key antibody targets have been identified in aiE. These include the N-methyl d-aspartate (NMda) receptors, voltage-gated potassium channel complexes—in particular leucine-rich glioma inactivated 1 (lGi1) and glu...
متن کاملAutoimmune Encephalitis.
The term autoimmune encephalitis is used to describe a group of disorders characterised by symptoms of limbic and extra-limbic dysfunction occurring in association with antibodies against synaptic antigens and proteins localised on the neuronal cell surface. In recent years there has been a rapidly expanding knowledge of these syndromes resulting in a shift in clinical paradigms and new insight...
متن کاملScreening Autoimmune Anti-neuronal Antibodies in Pediatric Patients with Suspected Autoimmune Encephalitis
BACKGROUND AND PURPOSE The aim of this study was to identify and describe the pediatric autoimmune encephalitis cases positive for anti-neuronal antibody tests. METHODS Screening of six anti-neuronal antibodies in 23 children with suspected autoimmune encephalitis was performed by cell-based indirect immunofluorescence test with patients' serum or cerebrospinal fluid. RESULTS Among the 23 c...
متن کاملO 19: Treatment and Porognosis of Autoimmune Encephalitis
AE is a serious medical condition in which the immune system attacks the brain, impairing function. With rapid diagnosis and appropriate treatment, many patients recover most or all functions. However, not all patients experience full recovery; with approximately 6% mortality and other patients who never regain significant brain and/or bodily functions. Autoimmune encephalitis can pro...
متن کاملO18: Autoimmune Encephalitis (Pathophysiology, Clinical Signs and Diagnos Tic Tests)
Autoimmune encephalitis is a difficult clinical diagnosis due to the similarities in the clini­cal, imaging and laboratory findings of many forms of autoimmune and infectious encephalitis. Autoimmune encephalitis involves several types: The first group includes the classic paraneo­plastic disorders associated with antibodies to intracellular antigens. The second group involves autoanti...
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ژورنال
عنوان ژورنال: Neurology - Neuroimmunology Neuroinflammation
سال: 2020
ISSN: 2332-7812
DOI: 10.1212/nxi.0000000000000682